Melanotan II Frequently Asked Questions

Melanotan II is a synthetic cyclic heptapeptide analogue of alpha-MSH, developed at the University of Arizona. It is a non-selective agonist of melanocortin receptors MC1R through MC5R, with research interest centred on its effects on pigmentation, appetite suppression, and sexual function. Peptides Pharma Melanotan II is formulated at >99% purity in a lyophilized vial.

Melanotan II binds to melanocortin receptors, particularly MC1R (involved in melanogenesis and skin pigmentation), MC3R and MC4R (involved in appetite regulation and sexual function). Activation of MC1R stimulates melanocytes to produce melanin, while MC4R activation is linked to the sexual function and appetite effects observed in research. These findings are from published preclinical and clinical studies.

Melanotan II is studied in research related to melanogenesis and pigmentation, appetite regulation, energy homeostasis, sexual dysfunction models, and melanocortin receptor pharmacology. Its non-selective receptor profile makes it a valuable tool for investigating the broader melanocortin system.

Peptides Pharma Melanotan II is manufactured to >99% purity in GMP-certified, ISO 7 cleanroom facilities. Every batch undergoes independent HPLC and mass spectrometry verification. A Certificate of Analysis is available for each production batch.

Lyophilized Melanotan II should be stored at -20°C for long-term storage or at 2-8°C for short-term use. Protect from direct light and moisture. Once reconstituted, refrigerate at 2-8°C and use within 28 days.

Reconstitute Melanotan II by slowly injecting bacteriostatic water down the inside wall of the vial. Allow the powder to dissolve gently without shaking. The volume of bacteriostatic water added determines the final peptide concentration for dosing calculations.

Reconstituted Melanotan II stored at 2-8°C with bacteriostatic water is typically stable for up to 28 days. Aseptic technique should be maintained when drawing doses to ensure the solution remains sterile throughout the usage period.

Yes. Peptides Pharma Melanotan II is supplied strictly for laboratory and research purposes. It is not approved as a medicine by any regulatory authority and is not intended for human therapeutic use. All research must comply with applicable regulations and guidelines.

Melanotan I (afamelanotide) is a linear analogue of alpha-MSH that selectively targets MC1R, primarily affecting pigmentation. Melanotan II is a cyclic peptide that acts on multiple melanocortin receptors (MC1R-MC5R), producing broader effects including appetite and sexual function modulation. The structural difference results in distinct receptor selectivity profiles.

Peptides Pharma ships Melanotan II in lyophilized form with cold-chain packaging to maintain stability during delivery. All orders include tracked shipping to ensure the product arrives in optimal condition for research use.